Faculty Of Pharmacy Publications List

  • S. Shabaan, T. A. Yousef, H. A. Althikrallah, Y. S. Al-Faiyz, I. Elghamry, M. Sharaky, R. Alnajjar and A. A. Al-Karmalawy, New J. Chem., 2024, https://doi.org/10.1039/D4NJ04376F
  • Huwaimel, B., Mohammed, H. A., Elkashlan, A. M., Alnajjar, R., Altamimi, O. A., Alorainan, M. M., … Abouzied, A. S. (2024). Unraveling the therapeutic potential of Satureja nabateorum extract: inducing apoptosis and cell cycle arrest through p53, Bax/Bcl-2, and caspase-3 pathways in human malignant cell lines, with in silico insights. Journal of Biomolecular Structure and Dynamics, 1–18. https://doi.org/10.1080/07391102.2024.2419863
  • Alsfouk, A.A., Faris, A., Cacciatore, I. and Alnajjar, R., Development of novel CDK9 and CYP3A4 inhibitors for cancer therapy through field and computational approaches. Frontiers in Chemistry, 12, p.1473398.https://doi.org/10.3389/fchem.2024.1473398
  • Sharif, S. I., Hitham, S., Mohammed, S., Tewfik, N., Inshasi, M., & Elshwehdi, N. (2024). Consumers satisfaction with pharmaceutical services in community pharmacies in Benghazi-Libya. International Journal of Basic & Clinical Pharmacology, 13(4), 444.https://doi.org/10.18203/2319-2003.ijbcp20241642
  • Althikrallah, H. A., Shaaban, S., Elmaaty, A. A., Ba-Ghazal, H., Almarri, M. N., Sharaky, M., … & Al-Karmalawy, A. A. (2024). Investigating the anti-inflammatory potential of N-amidic acid organoselenium candidates: biological assessments, molecular docking, and molecular dynamics simulations. RSC advances, 14(44), 31990-32000.
  • Al-Mathkuri, T. S., Al-Jubori, H. M., Majed, A. A., Moker, M. H., Santali, E., & Alnajjar, R. (2024). Synthesis, Breast Cancer Activity, Molecular Docking and Dynamic Simulation of 1, 4-Dihydropyridine Derivatives. Journal of Molecular Structure, 139704. https://doi.org/10.1016/j.molstruc.2024.139704
  • Elsbaey, M., Igarashi, Y., Alnajjar, R., Darwish, K. M., & Miyamoto, T. (2024). Nuciferol C, a new sesquineolignan dimer from Cocos nucifera L.: bioactivity and theoretical investigation. RSC Advances, 14(36), 25900-25907.https://doi.org/10.1039/d4ra02940b.
  • Faris, A., Cacciatore, I., Alnajjar, R., Aouidate, A., AL Mughram, M., & Elhallaoui, M. Computational Insights into Rational Design and Virtual Screening of Pyrazolopyrimidine Derivatives Targeting Janus Kinase 3 (JAK3). Frontiers in Chemistry, 12, 1425220. https://doi.org/10.3389/fchem.2024.1425220.
  • Mohamad, K. A., Alhallouji, O. S., Alabbar, I. H., Alfitori, A. M., & Sharif, S. I. (2024). Cost analysis study of price variation among the various brands of proton pump inhibit available in Benghazi-Libya. International Journal of Basic & Clinical Pharmacology, 13(4), 464–468. https://doi.org/10.18203/2319-2003.ijbcp20241645
  • Sharif, S. I., Hitham, S., Mohammed, S., Tewfik, N., Inshasi, M., & Elshwehdi, N. (2024). Consumers satisfaction with pharmaceutical services in community pharmacies in Benghazi-Libya. International Journal of Basic & Clinical Pharmacology, 13(4), 444–449. https://doi.org/10.18203/2319-2003.ijbcp20241642
  • Aisha Alfituri, Alasbily H, Fatima Alanieze, Sarah Bujazia, Talal Aboutrabah. Complications Following COVID-19 Infection or Vaccination in Libyan International Medical Universit Students and Their Families . Alq J Med App Sci [Internet]. 2024 Mar. 24 [cited 2024 May 27];:213-21. Available from: https://www.journal.utripoli.edu.ly/index.php/Alqalam/article/view/520
  • Alfituri, A. M., Elhamdy, F. A., Alagory, N., Ateeq, A. R., & Mustafa, A. B. (2024). Pharmacoepidemiologic Study of the Complementary and Alternative Medicine (CAM) Use in Patient with Cancer in Benghazi, Libya. MISJ-International Journal of Medical Research and Allied Sciences, 2(02), 46-61. https://doi.org/10.5281/zenodo.10936482
  • El-Damasy, A.K.; Kim, H.J.; Al-Karmalawy, A.A.; Alnajjar, R.; Khalifa, M.M.; Bang, E.-K.; Keum, G. Identification of Ureidocoumarin-Based Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors via Drug Repurposing Approach, Biological Evaluation, and In Silico Studies. Pharmaceuticals 2024, 17, 427. https://doi.org/10.3390/ph17040427
  • Halat, D. H., Al-Jumaili, A. A., Ahmed, K. K., Rahal, M., Hamad, A., Darwish, R. M., … & Alsharif, N. Z. (2024). Academic Entitlement Among Pharmacy Students in the Arab World: A Multi-National Exploratory Study. American Journal of Pharmaceutical Education, 88(2), 100640. DOI: 10.1016/j.ajpe.2023.100640.
  • Kras, J., Mikulska, M., Allnajar, R., & Kula, K. (2024). Unsuccessful synthesis of individual 1, 1-dinitroethene. DOI: 10.58332/scirad2024v3i1a02
  • Faris, A., Cacciatore, I., Alnajjar, R., Hadni, H., Aouidate, A., A Mothana, R., … & Elhallaoui, M. Revealing Innovative JAK1 and JAK3 Inhibitors: A Comprehensive Study Utilizing 2D-QSAR, 3D-Pharmacophore Screening, Molecular Docking, Molecular Dynamics, and MM/GBSA Analyses. Frontiers in Molecular Biosciences, 11, 1348277.  https://doi.org/10.3389/fmolb.2024.1348277
  • Alshami, H. A. A., Hussein, M. S., Habib, H. A., Al-Mahdawi, R., & Bukhatwa, S. A. (2023). Advanced Pharmacy Practice Experience at Libyan International Medical University during COVID-19 Era: PharmD Preceptors’ and Students’ Perception toward Virtual Training. Medical Research Archives, 11(12).  DOI: https://doi.org/10.18103/mra.v11i12.4786
  • Sharif, S. I., ALotaibi, A., ALGhanim, L., Lahmed, N., Abdelrazig, K., Bugrain, A., & Kashbour, A. (2023). Preference of Health, Non-Health Care Students and Practicing Pharmacists of Brand or Generic and Imported and Locally Made Medicines.
  • Hamrouni, A. M., Sharif, S. I., Abduelkarem, A. R., & Hassanein, M. M. (2023). Integration of Clinical Pharmacy Services in Primary Healthcare in the United Arab Emirates: Indicators and Impacts. Pharmacy Practice, 21(4), 1-6. https://www.pharmacypractice.org/index.php/pp/article/view/2872/1130
  • Suleiman I. Sharif, Salma A. Bukhatwa, Khalid A. Mohamad, Hiba S. AlAroushi, Hassan A.S. Ali and Rubian S. Sharif (2023) Review of mentoring in Higher Education. Mediterr JPharm Pharm Sci. 3 (4): 13-17. https://doi.org/10.5281/zenodo.10051646, https://medjpps.com/mjpps/uploads/topics/17039551822393.pdf
  •  D. N., Aiamame, M. I., Hamad, A. I., Almhashhash, A. O., Bayou, R. A., & Alshami, H. A. Uric acid and glucose metabolism in uncomplicated Libyan diabetic patients , https://doi.org/10.5281/zenodo.8327189Shateila, https://medjpps.com/mjpps/uploads/topics/16960938802028.pdf
  • Al-Karmalawy AA, Mousa MHA, Sharaky M, Mourad MAE, El-Dessouki AM, Hamouda AO, Alnajjar R, Ayed AA, Shaldam MA, Tawfik HO. Lead Optimization of BIBR1591 To Improve Its Telomerase Inhibitory Activity: Design and Synthesis of Novel Four Chemical Series with In Silico, In Vitro, and In Vivo Preclinical Assessments. J Med Chem. 2023 Dec 20. doi: 10.1021/acs.jmedchem.3c01708. Epub ahead of print. PMID: 38117230. https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01708 
  • Faris A, Alnajjar R, Guo J, AL Mughram MH, Aouidate A, Asmari M, Elhallaoui M. Computational 3D Modeling-Based Identification of Inhibitors Targeting Cysteine Covalent Bond Catalysts for JAK3 and CYP3A4 Enzymes in the Treatment of Rheumatoid Arthritis. Molecules. 2024; 29(1):23. https://doi.org/10.3390/molecules29010023
  • Salsabeel Salah, Najat Sami, Sarah Ali, Teemah-Alrahman Khalid, and Radwan Alnajjar, Natural Products as Potential Inhibitors of FLT3 for Acute Myeloid Leukemia: HTVS, Docking, and Molecular Dynamic Simulation – Scientiae Radices. (2023, December 5). Scientiae Radices.  doi: 10.58332/scirad2023v2i4a03.
  • Ashraf K. El-Damasy, Jong Min Oh, Hyun Ji Kim, Seul-Ki Mun, Ahmed A. Al-Karmalawy, Radwan Alnajjar, Yu-Jeong Choi, Jong-Jin Kim, Ghilsoo Nam, Hoon Kim, Gyochang Keum, Novel coumarin benzamides as potent and reversible monoamine oxidase-B inhibitors: Design, synthesis, and neuroprotective effects, Bioorganic Chemistry, 2023, https://doi.org/10.1016/j.bioorg.2023.106939.
    https://www.sciencedirect.com/science/article/pii/S0045206823006004?via%3Dihub
  • Ahmed A. Al-Karmalawy, Radwan Alnajjar, Ayman Abo Elmaaty, Faizah A. Binjubair, Sara T. Al-Rashood, Basma S. Mansour, Ahmed Elkamhawy, Wagdy M. Eldehna & Khaled Ahmed Mansour (2023) Investigating the promising SARS-CoV-2 main protease inhibitory activity of secoiridoids isolated from Jasminum humile; in silico and in virto assessments with structure-activity relationship, Journal of Biomolecular Structure and Dynamics, DOI: 10.1080/07391102.2023.2240419
  • Khelfaoui, H., Harkati, D., Saleh, B. A., Hewitt, N. L., Alnajjar, R., & El-Hiti, G. A. (2023). In-Silico Evaluation, Chemical Reactivity, and Covalent Docking Study of Various Quinazolines and Pyridopyrimidines as Inhibitors for the Epidermal Growth Factor Receptor. Polycyclic Aromatic Compounds, 1-26, https://doi.org/10.1080/10406638.2023.2237628.
  • Bukhatwa, S. ., A elmabsout, A. ., Elhouseni, N. A. ., Bennaser, H. B. ., Elfergany, S. M..,.. Kashbour, A. ., & Alyamani , E. . (2023). Psychostimulant Drugs Abuse among Libyan Medical Students. British Journal of Multidisciplinary and Advanced Studies, 4(1), 1–10. https://doi.org/10.37745/bjmas.2022.0085.

  • Farouk, F., Elmaaty, A. A., Elkamhawy, A., Tawfik, H. O., Alnajjar, R., Abourehab, M. A.,… & Al‐Karmalawy, A. A. (2023). Investigating the potential anticancer activities of antibiotics as topoisomerase II inhibitors and DNA intercalators: in vitro, molecular docking, molecular dynamics, and SAR studies. Journal of Enzyme Inhibition and Medicinal Chemistry, 38(1), 2171029.

  • Al-Karmalawy, A. A., El-Gamil, D. S., El-Shesheny, R., Sharaky, M., Alnajjar, R., Kutkat, O. & Zakaria, M. Y. (2023). Design and statistical optimisation of emulsomal nanoparticles for improved anti-SARS-CoV-2 activity of N-(5-nitrothiazol-2-yl)-carboxamido candidates: in vitro and in silico studies. Journal of Enzyme Inhibition and Medicinal Chemistry, 38(1), 2202357.

  • Son, S., Elkamhawy, A., Gul, A. R., Al‐Karmalawy, A. A., Alnajjar, R., Abdeen, A. & Lee, K. (2023). Development of new TAK-285 derivatives as potent EGFR/HER2 inhibitors possessing antiproliferative effects against 22RV1 and PC3 prostate carcinoma cell lines. Journal of Enzyme Inhibition and Medicinal Chemistry, 38(1), 2202358.

  • Kandeil, A., Abi-Said, M., Badra, R., El-Shesheny, R., Al-Karmalawy, A. A., Alnajjar, R., … & Kayali, G. (2023). Detection of Coronaviruses in Bats in Lebanon during 2020. Pathogens, 12(7), 876.

  • Bukhatwa, S. A., Elmabsout, A. A., Jaber, N. E., Tagoeri, K. M., Tagoeri, A. M., Zgogo, R., & Kashbour, A. (2023). Drugs Prescribing Trends in Three Polyclinics in Benghazi-Libya 2020. European Journal of Medical and Health Sciences, 5(2), 12-16.

  • Elmaaty, A. A., Al‐Karmalawy, A. A., Nafie, M. S., Shamaa, M. M., Zaki, I., Alnajjar, R., & Zakaria, M. Y. (2023). Experimental design of D-α-tocopherol polyethylene glycol 1000 succinate stabilized bile salt based Nano-vesicles for improved cytotoxicity and bioavailability of colchicine binding site inhibitor Candidates: In Vitro, in silico, and pharmacokinetic studies. International Journal of Pharmaceutics, 640, 122980. https://doi.org/10.1016/j.ijpharm.2023.122980.
  • Eissa KI, Kamel MM, Mohamed LW, Doghish AS, Alnajjar R, Al-Karmalawy AA, Kassab AE. Design, synthesis, and biological evaluation of thienopyrimidine derivatives as multifunctional agents against Alzheimer’s disease. Drug Dev Res. 2023 Apr 17. doi: 10.1002/ddr.22064.
 
  • Elkamhawy, A., Son, S., Lee, H. Y., El-Maghrabey, M. H., Hamd, M. A. E., Alshammari, S. O., & Lee, K. (2022). Design, synthesis, biological evaluation, and molecular dynamics studies of novel lapatinib derivatives. Pharmaceuticals, 16(1), 43.

  • Hussein, M., Alshami, H., Amer, E., & Eltarhoni, A. (2022). The Impact of Pharmaceutical Care Intervention on Health-Related Quality of Life in Hemodialysis Patients in different centers in Benghazi.

  • Garalla H, Elnaas A, Shalgami R, Mohsen A. Prevalence of Kidney Stone Diseases in Benghazi; Libya. Current Opinion, 2022; 2(6):208–212. Prevalence of Kidney Stone Diseases in Benghazi; Libya | Current Opinion
  • Hussein ME, Mohamed OG, El-Fishawy AM, El-Askary HI, Hamed AA, Abdel-Aziz MM, Alnajjar R, Belal A, Naglah AM, Almehizia AA, Al-Karmalawy AA, Tripathi A, El Senousy AS. Anticholinesterase Activity of Budmunchiamine Alkaloids Revealed by Comparative Chemical Profiling of Two Albizia spp., Molecular Docking and Dynamic Studies. Plants. 2022; 11(23):3286. Anticholinesterase Activity of Budmunchiamine Alkaloids Revealed by Comparative Chemical Profiling of Two Albizia spp., Molecular Docking and Dynamic Studies
  • Elmaaty A, Eldehna W, Khattab M, Kutkat O, Alnajjar R, El-Taweel A, Al-Rashood S, Abourehab M, Binjubair F, Saleh M, et al. Anticoagulants as Potential SARS-CoV-2 Mpro Inhibitors for COVID-19 Patients: In Vitro, Molecular Docking, Molecular Dynamics, DFT, and SAR Studies. Int. J. Mol. Sci. 2022; 23(20):12235. https://www.mdpi.com/1422-0067/23/20/12235
  • El-Shintiri N, Elsharksi A, Mohamed I, Elmabsout A, Elathram S, Aldressi M, Aboshawesh N. Impact of energy drink consumption on pattern and quality of sleep among students in Libyan International Medical University. Mediterr J Pharm Pharm Sci. 2022; 2(3): 24-30. https://doi.org/10.5281/zenodo.7115154
  • Elgadi A, Mahmoud A, Alabidi A, Albarghathi Z, Mohammed N, Mohamed I, Bukhatwa S, Elmabsout A. Evaluate the effectiveness and safety of proton pump inhibitors (PPIs) in the treatment of upper GIT disorders. World Journal of Advanced Research and Reviews. 2022; 13(01): 027–037, https://wjarr.com/content/evaluate-effectiveness-and-safety-proton-pump-inhibitors-ppis-treatment-upper-git-disorders
  • Al-Jumaili AA, Sherbeny F, Elhiny R, Hijazi B, Elbarbry F, Rahal M, Bukhatwa S, Khdour M, Thomas D, Khalifa S, Hamad A. Exploring job satisfaction among pharmacy professionals in the Arab world: a multi-country study. Int J Pharm Pract. 2022;30(2): 160-168. https://academic.oup.com/ijpp/article-abstract/30/2/160/6581944?redirectedFrom=fulltext&login=false
  • Sassi M, Al’asmae Y, Addal NE, Elmabsout A, Hussin H, Elmahdi I, Bukhatwa S. Dyslipidemia and Vitamin D Status in Diabetic Patients. International Journal of Current Science Research and Review. 2022; 5(1): 50-57. https://ijcsrr.org/single-view/?id=4918&pid=4889
  • Alshami H, Hussein M, Habib H, Lawgaly S, Rajab A, Elshaab W, Elhemri M, Bukhatwa S. Pharmacy Experiential Training During COVID-19: A STORY OF INSPIRATION. MyDispense Symposium.  Prato centre, Toscany, Italy. July 2022
  • Alshami H, Hussein M, Abdelraziq K, Elnour S, Habib H, Elmehdawi R, Bukhatwa S. PharmD students’ perception toward using Mydispense during virtual training at Libyan International Medical University. MyDispense Symposium, Prato centre, Toscany, Italy. July 2022
  • Elzway M, Almalky M, Elmabsout A, Mansour R, Elmahdi I, Bukhatwa S. Effect of lipid lowering agents on lipid profile, blood glucose and Glycated hemoglobin in DM patients. International Journal of Pharmaceutical Research and Applications. 2021; 6(6): 1226-1233

www.ijprajournal.com/current-issue.php?issueid=35&title=Effect%20of%20lipid%20lowering%20agents%20on%20lipid%20profile

  • Elhashani A, Shahbaz J, Shaqami S, Burgeia A, Garalla H. CLINICO-PATHOLOGICAL PARAMETER IN THYROID CARCINOMA SUBTYPES. International Journal of Science and Research (IJSR). 2021; 10(11):1404-1407.

https://www.ijsr.net/get_abstract.php?paper_id=SR211125235408

  • Habib H, Alshami H, Boamoud E, Tashani H, Shalgami S. Effect of Angiotensin Converting Enzyme Inhibitors on Health-Related Quality of Life in Libyan Patients with Hypertension. Mediterranean Journal of Pharmacy and Pharmaceutical Science. 2021; 1(3):8-11.

https://medjpps.com/mjpps/effect-of-angiotensin-converting-enzyme-inhibitors-on-health-related-quality-of-life-in-libyan-patients-with-hypertension

  • Amraja E, Buras Ali R, Elsherif A, Hussein M, Kattab H. The Difference between the Reports from Asthmatic Children and Their Parents about the Effect of Asthma on Their Quality of Life in Pediatric Hospital-Benghazi-Libya. International journal of advanced research (IJAR). 2021; 9(6):01-08.

https://www.journalijar.com/article/37288/the-difference-between-the-reports-from-asthmatic-children-and-their-parents-about-the-effect-of-asthma-on-their-quality-of-life-in-pediatric-hospital-benghazi-libya/

  • Hussin H, Mohamed I, Alobidy S, Bosafita F. Effect of Metformin on Weight Reduction among Diabetic and Non-Diabetic Obese Patients. International journal of advanced research (IJAR). 2021; 9(02):893-897.

https://www.journalijar.com/article/36326/effect-of-metformin-on-weight-reduction-among-diabetic-and-non-diabetic-obese-patients/

  • Fathi H, Bukhatwa S, Ambarek M, Elfakhri M, Altawatya A, Senini R, Kashbour A, Bograin A, Hussein M, Elnoor S, Buzariba E, Hussin H, Elmahdi I, Sharkasi A. PharmD Students’ Perceptions on Structured Peer Assessment Process Within Problem Based Learning Sessions. Medical education conference (MEC), 2019, Benghazi, Libya.

http://repository.limu.edu.ly/handle/123456789/1275

  • Altawatya A, Bukhatwa S, Bograin A, Kashbour A, Elmahdi I, Hussein M, Buzariba E, Senini R, Sharkasi A, Elnoor S, Hussin H. Learning Environment Perceptions of PBL-Taught PharmD Students at The Libyan International Medical University, Benghazi, Libya. Medical education conference (MEC), 2019, Benghazi, Libya.

http://repository.limu.edu.ly/handle/123456789/1274

  • Helal F, Faraj A, Kablan N, Elfakhri M, Bukhatwa S. Prevalence of Vitamin D Deficiency among Overweight and Obese Libyan Females. Pharmacy & Pharmacology International Journal. 2018; 6(6):453-457.

https://medcraveonline.com/PPIJ/prevalence-of-vitamin-d-deficiency-among-overweight-and-obese-libyan-females.html

  • Bukhatwa S, Elfakhri M. The First PharmD Program in Libya. Libyan International Medical University Journal. 2019; 4(2):45-48.

https://journal.limu.edu.ly/article.asp?issn=2519-139X;year=2019;volume=4;issue=2;spage=45;epage=48;aulast=Bukhatwa

  • Bukhatwa S, Elmahdi I, Buzariba E, Maghoud H, Alathram N, Buanz A, Habib H, Saleh M, Bugrain A, Mohamed N, Sinini R, El Naili E, Ali N, Elmugassabi A, Elfaidy T, Eltyb S, Baraka M, Moustafa M, Labouta I, Al-Tawaty A, Elfakhri M, Ambarak M. Integrating Pharmacy Practice into First Year PharmD Curriculum. Pharmacy practice conference. 2017.

http://repository.limu.edu.ly/handle/123456789/67

  • Elfakhri M, Bukhatwa S. Higher education in Libya: Challenges and Future Plans. Libyan International Medical University Journal. 2016; 1:27-34.

https://journal.limu.edu.ly/article.asp?issn=2519-139X;year=2016;volume=1;issue=1;spage=27;epage=34;aulast=El-Fakhri;type=0

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